MOTS-C
The mitochondrial peptide of metabolism and energy.
Produced naturally in the mitochondria, it drew interest for its role in regulating metabolism, glucose and the response to exercise.
What is it?
A peptide encoded by mitochondrial DNA —one of the few that originates directly in the mitochondria—. It helps regulate how cells produce and use energy.
How does it work?
It takes part in the communication between the mitochondria and the cell nucleus, supporting adaptation to metabolic stress and a more efficient use of glucose and energy.
What science is researching
Observed results
Results may vary from person to person and depend on the context of the study.
- Better glucose utilization in experimental models
- Greater efficiency of energy metabolism
- Potential improvement in the response to exercise
- Interest in its role in metabolic health and aging
What it does NOT do
- It does not replace a balanced diet or exercise
- It does not guarantee weight loss or performance
- It is not approved as a metabolic treatment
- It remains a research compound
Is it for you?
If you're interested in learning about:
- Energy metabolism
- Mitochondrial function
- Glucose utilization
- Adaptation to exercise
- Healthy aging
Quick summary
It is one of the first discovered peptides to originate from mitochondrial DNA, showing that mitochondria don't just produce energy: they also take part in cellular communication.
Related in Metabolism